Spider-Man: Homecoming is the first entry in the Marvel Cinematic Universe featuring the web slinger. This film is unique as it is a product of a film deal between Sony Pictures ( who has the film rights to Spider-Man and associated characters) and Disney. It was no secret that when Sony was developing The Amazing Spider-Man 2, they were also trying to set up a Sinister Six movie. The Sinister Six is a collective of six (obviously) of Spider-Man’s deadliest enemies. That film shoehorned that aspect into the film and ultimately suffered because of it. That is partially why the deal between Sony and Disney was made regarding Spider-Man. But now we are starting to see sides where a Sinister Six can naturally develop.
One of the worst trends about superhero movies is the villain almost always dies by the end of the film. The Marvel Cinematic Universe have been no different in this aspect. Another trend within the MCU concerning the villains is the lack of depth. I can’t tell you what Yellowjacket’s motivations in Ant-Man were. So hiring a great actor in Michael Keaton in this type of role would be a shame.
Keaton plays Adrian Toomes aka The Vulture. It is also known that Spider-Man villains The Shocker and Tinkerer are in the film as well. How big of a role that they play in the film is up in the air at this moment. But it is known that Toomes is in cahoots with them. Toomes could stay alive by the end of the film and ultimately be the one to form The Sinister Six.
Now this is all speculation because I have no idea about the specifics of the deal between Sony and Disney is. But it is something better than the previously rushed aspect. Time will tell.